Sustained arm visiting by nondeprived, nonrewarded rats in a radial maze

Within-Trial Dynamics of Radial Arm Maze Performance in Rats

The behavior of rats white solving a 12-arm radial maze was investigated using measures of response bias, choice latencies, and behavioral organization. Response bias decreased as a function of choice number, while the amount of time spent on the center platform between choices increased substantially during the last few choices. This increase in time between choices was largely accounted for b...

3,4 methylenedioxymethamphetamine (ecstasy) impairs eight-arm radial maze performance and arm entry pattern in rats.

The recreational use of 3,4 methylenedioxymethamphetamine (ecstasy) in humans has been associated with memory impairment. The present study examined whether ecstasy impairs short- and long-term working memory and the pattern of arm entries in rats tested in the 8-arm radial maze with a 2-hr delay. After completing the training session, the rats were given a single dose of ecstasy (1, 2, or 3 mg...

Spatial memory in pigeons on a four-arm radial maze.

Nigella sativa Oil Enhances the Spatial Working Memory Performance of Rats on a Radial Arm Maze

Nigella sativa, an established historical and religion-based remedy for a wide range of health problems, is a herbal medicine known to have antioxidant and neuroprotective effects. This present study investigated the effect of Nigella sativa oil (NSO) administration on the spatial memory performance (SMP) of male adult rats using eight-arm radial arm maze (RAM). Twelve Sprague Dawley rats (7-9 ...

Chlordiazepoxide specifically impairs nonspatial reference memory in the cued radial arm maze in rats.

Anxiolytic benzodiazepines, at low doses, reportedly impair the radial arm maze with nonspatial visual/tactile but not spatial cues. We replicated the former result controlling for changes in drug state and cue effectiveness. Rats learned an eight-arm radial maze with reward in only four arms. The reward varied in spatial position from trial to trial but was always cued by a piece of sandpaper ...